Lion’s Mane

The fruiting body is the mushroom itself — the part that accumulates the highest concentrations of hericenones and erinacines, the compounds that support NGF production. The mycelium is the root network; it also contains beneficial compounds, but lower-quality supplements grow mycelium on grain and end up with a product that is primarily starch with very little active mushroom content. Glenari uses both fruiting body and mycelium — not mycelium-on-grain. Our formula is standardized to 40% polysaccharides (400mg per serving), which is third-party verified on every lot. That number is what matters — it's proof of potency, not just a label claim.

Take two capsules daily — that delivers 1,000mg of Lion's Mane extract (standardized to 400mg active polysaccharides). Most people take them in the morning with water, either before or with breakfast — Lion's Mane is non-stimulating, so it won't disrupt sleep if taken later, but morning use aligns with the natural peak of mental performance during the day. You don't need to cycle it on and off; daily use is both safe and the most effective way to build consistent support for cognitive function.

Every lot is tested by an ISO/IEC 17025 accredited independent laboratory using ICP-MS testing for heavy metals. Our Certificate of Analysis (COA) shows total heavy metals at 0.32µg per serving — against an FDA allowable limit of 20µg. Our polysaccharide content came back at 401.78mg per serving, exceeding our 400mg label claim. Our manufacturing facility is GMP certified and is FDA Registered.

Lion's Mane is generally recognized as safe (GRAS) when consumed daily as directed. Side effects are rare and typically mild — occasional digestive sensitivity in the first few days as your body adjusts, which usually resolves on its own. If you have a known allergy to mushrooms, avoid it. If you're pregnant, breastfeeding, or on prescription medication (particularly immunosuppressants or blood thinners), speak with your healthcare provider first. There is no evidence of dependency or tolerance — you can take it long-term without concern about needing to increase your dose to maintain the same effect.